Reprogramming of the Genome: Applications of CRISPR-Cas in Non-mammalian Systems

Reprogramming of the Genome: Applications of CRISPR-Cas in Non-mammalian Systems, represents the collation of chapters written by eminent scientists worldwide. CRISPR-Cas9 system is an RNA-mediated immune system of bacteria and archaea that protects from bacteriophage infections. It is one of the revolutionized technologies to uplift biology to the next stages. It is a simple, rapid, precise, and cost-effective tool for genome editing and regulation of a wide range of organisms. It has gained scientific and public attention worldwide. This volume covers several lower and model organisms that have been used for genome editing for creating a model for understanding of the molecular mechanism, disease model, removal of bacteria, virus, fungi, protozoans, insects, among others. This book is a key source of information available in a single volume. This book will be useful for not only beginners in genome engineering, but also students, researchers, scientists, policymakers, and stakeholders interested in harnessing the potential of reprogramming of the genomes in several areas. Offers basic understanding and a clear picture of genome editing CRISPR-Cas systems in different organismsExplains how to create an animal model for disease diagnosis/research and reprogram CRISPR for removal of virus, bacteria, fungi, protozoan and many moreDiscusses the advances, patents, applications, challenges and opportunities in CRISPR-Cas9 systems in basic sciences, biomedicine, virology, bacteriology, molecular biology and many more INDICE: 1. An Introduction and applications of CRISPR-Cas Systems Vijai Singh 2. History, evolution and classification of CRISPR-Cas associated systems Nisheeth Agrawal and Radhika Gupta 3. CRISPR based bacterial genome editing and removal of pathogens Lakkakula Satish 4. CRISPR based genome editing and removal of human viruses Yuan-Chuan Chen 5. CRISPR based development of RNA editing and diagnostic platform Lakkakula Satish 6. CRISPR based pathogenic fungus genome editing for control of infections Takayuki Arazoe 7. Genome engineering in insects for control of vector borne diseases Stanislaus Antony Ceasar and V. Edwin Hillary 8. Development of insect cell line using CRISPR technology Deepak Balaji Thimiri Govindaraj 9. CRISPRing protozoan parasites to better understand the biology of diseases Abhisheka Bansal 10. CRISPR based genome editing of Caenorhabditis elegans Arumugam Kamaladevi 11. CRISPR based genome editing of zebra fish Preeti Sharma 12. Using CRISPR-Cas9 based genome engineering tools in Drosophila melanogaster Deepti Trivedi 13. CRISPR interference and its applications Amir Pandi 14. CRISPR-Cas systems: Challenges and Future Prospects Nisarg Gohil, Gargi Bhattacharjee and Vijai Singh 15. Patents and technology transfer in CRISPR technology Deepak Balaji Thimiri Govindaraj

• ISBN: 978-0-323-85321-7
• Editorial: Academic Press
• Encuadernacion: Cartoné
• Páginas: 300
• Fecha Publicación: 01/04/2021
• Nº Volúmenes: 1
• Idioma: Inglés