Organic Synthesis, Fifth Edition provides a reaction-based approach to this important branch of organic chemistry. Updated and accessible, this eagerly-awaited revision offers a comprehensive foundation for graduate students coming from disparate backgrounds and knowledge levels, to provide them with critical working knowledge of basic reactions, stereochemistry and conformational principles. This reliable resource uniquely incorporates molecular modeling content, problems, and visualizations, and includes reaction examples and homework problems drawn from the latest in the current literature.? There have been advancements in organic reactions, particularly organometallic reactions, and there is a need to show how these advancements have influenced current organic synthesis. The goal is to revise and update the examples of reaction examples taken from the synthesis literature from about 2017-2023. The reactions illustrate those that are used most often in modern organic synthesis, but recent examples will show their current relevance.? Where new approaches and new reactions have been developed for organic synthesis, examples will be added as new material. Provides new content, reaction examples, and study problems from recent research?Features improved organization, new art, and new chapter content on process chemistry and green organic chemistryIncludes revised homework for each chapter, with new examples and questions? INDICE: 1.?Retrosynthesis, Stereochemistry, And Conformations 2. Acids And Bases and Addition Reactions 3. Functional Group Exchange Reactions 4. Acids, Bases, And Functional Group Exchange Reactions 5.?Functional Groups Exchange Reactions 6. Functional Group Exchange Reactions. Oxidations 7. Functional Group Exchange Reactions. Reductions 8. Synthetic strategies 9. Functional Group Exchange Reactions.? Hydroboration 10. Functional Group Exchange Reactions 11. Carbon-Carbon Bond-Forming Reactions.?? Cyanide, Alkyne Anions, Grignard Reagents, and Organolithium Reagents 12. Carbon-Carbon Bond-Forming Reactions.?? Stabilized Carbanions, Organocuprates, and Ylids 13. Carbon-Carbon Bond-Forming Reactions.?? Enolate Anion 14. Pericyclic Reactions.? The Diels-Alder Reaction 15. Pericyclic Reactions: [m+n]-Cycloadditions, Sigmatropic Rearrangements,?? Electrocyclic and Ene Reactions 16. Carbon-Carbon Bond-Forming Reactions.?? Carbocation and Oxocarbenium Ion Intermediates 17. Formation Of Carbon-Carbon Bonds Via Radicals and Carbenes 18. Metal-Mediated, Carbon-Carbon Bond-Forming Reactions 19. Combinatorial And Process Chemistry
- ISBN: 978-0-443-15867-4
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 1100
- Fecha Publicación: 01/09/2024
- Nº Volúmenes: 1
- Idioma: Inglés