This book is written by leading researchers in the fields about the intersection of genetics and metabolomics which can lead to more comprehensive studies of inborn variation of metabolism. INDICE: Introduction.- Pre-conditions for high quality biobanking in largehuman epidemiological cohorts for metabolomics and other -omics studies.- Assay Tools for Metabolomics.- Statistical methods in genetic and molecular epidemiology and their application in studies with metabolic phenotypes.- Ultrahighresolution mass spectrometry based non-targeted microbial metabolomics.- etabolomic systems biology of protozoan parasites.- Mouse genetics and metabolic mouse phenotyping.- Metabolomics in animal breeding.- Metabolomics applicationsin human nutrition.- Metabolomics for the individualized therapy of androgen deficiency syndrome in male adults.- Systems biology resources arising from the human metabolome project.- Understanding cancer metabolism through global metabolomics.- Genetic and metabolic determinants of fatty acid chain length anddesaturation, their incorporation into lipid classes and their effects on risk of vascular and metabolic disease.- Mapping metabolomic quantitative trait loci (mQTL) – A link between metabolome-wide association studies and systems biology.- Metabolic traits as intermediate phenotype.- Genome-wide association studies with metabolomics.- Systems biology meets metabolism.- Index.
- ISBN: 978-1-4614-1688-3
- Editorial: Springer
- Encuadernacion: Cartoné
- Fecha Publicación: 28/06/2012
- Nº Volúmenes: 1
- Idioma: Inglés