Medical Epigenetics is an inclusive volume on the medical aspects of epigenetics with a focus on human systems, epigenetic disease that affect these systems, and modes of treating epigenetic-based disorders and diseases. This book provides stand-alone coverage of all human systems relevant to epigenetic maladies and all major aspects of medical epigenetics. It is useful not only to physicians, nurses, medical students, and many others directly involved with healthcare, but also investigators in life sciences, biotech companies, graduate students, and all others who are interested in more applied aspects of epigenetics. The expansion of the field of epigenetics has brought a wealth of information with respect to variations in phenotypes that are heritable. In addition, many advances have emerged that have shown epigenetic aberrations as central to a number of diseases and disorders that were previously thought to be manifested primarily through genetic factors. Along with the remarkable studies that have been made in our understanding of epigenetic-based diseases and disorders has come new information that allows treatments that target these many epigenetic aberrations. Medical Epigenetics brings all of this knowledge together to comprehensively review the state of medical epigenetics in one defining volume. The basic design of Medical Epigenetics is to lead the reader from the fundamental mechanisms of epigenetics as they apply to humans through approaches for treating epigenetic-based diseases. This book begins with the basic tenets of epigenetics in human systems and progresses through general medical aspects of epigenetics, epigenetics or system disorders, multi-system medical epigenetics, pharmacology of epigenetics, and therapeutic epigenetics. Medical Epigenetics closes with a chapter on future prospects in medical epigenetics. This book is by far the most complete book in the area of applied epigenetics. Focuses on practical and applied aspects of medical epigeneticsIncludes peer-reviewed chapters with up-to-date coverage of emerging topics in medical epigenetics by leading expertsAppeals to those interested in fundamental epigenetics and inheritance, as well as those with more clinical interests including practicing physicians and other health care professionalsCovers the basic tenets of epigenetics in human systems and progresses through general medical aspects of epigenetics, epigenetics or system disorders, multi-system medical epigenetics, pharmacology of epigenetics, and therapeutic epigenetics INDICE: Section I: Overview1. Medical Epigenetics: An OverviewSection II: Basic Principles of Epigenetics2. DNA Methylation: Basic Principles 3. An Overview of Histone Modifications4. Basic Principles of Non-coding RNA in Epigenetic ProcessesSection III: General Medical Aspects of Epigenetics5. Epidemiological Epigenetics in Medicine6. Life-style and Preventive Medical Epigenetics 7. Environmental Medical Epigenetics8. Behavioral Medical Epigenetics9. Medical Epigenetics in Twins10. Epigenetic Biomarkers of Disease11. Prognostic Epigenetics12. Computational Medical EpigeneticsSection IV: Epigenetics of System Disorders 13. Immune System Disorders and Epigenetics14. Pulmonary Disease Epigenetics15. Cardiovascular Disorders and Epigenetics16. Epigenetics of Gastrointestinal Diseases17. Epigenetics of Skin Disorders18. Rheumatology and Bone Disease Epigenetics19. Epigenetics of Muscle Disorders20. Epigenetics of Neurological Disorders21. Endocrine Disorder Epigenetics22. Reproductive Disease Epigenetics23. Ocular Epigenetics in MedicineSection V: Multi-system Medical Epigenetics24. Pediatric Diseases and Epigenetics25. Epigenetics of Geriatric Disorders26. Epigenetics of Infectious Diseases27. Solid Tumor Epigenetics28. Epigenetics of Hematological and Lymphatic Cancers29. Epigenetics of Metastasis30. Sports Epigenetics31. Transgenerational Epigenetics in MedicineSection VI. Pharmacology of Epigenetics32. Toxicology and Epigenetics33. PharmacoepigenomicsSection VII: Therapeutic Epigenetics34. Therapeutics and DNA Methylation Inhibitors35. Histone Deacetylase Inhibitors in Medical Therapeutics36. NAD-dependent Deacetylases and Medical Therapy37. Therapeutics of Histone Acetyltransferase Inhibitors 38. Therapeutics of Epigenetic-based RNA molecules39. Natural Epigenetic-modifying Molecules in Medical Therapy40. Combinatorial Therapeutics and Epigenetics41. Epigenetics of Pain Management42. Personalized Epigenetic Medicine43. Epigenetics of Regenerative Medicine44. Stem Cell Epigenetics in Medical TherapySection VIII: Medical Epigenetics: Future Prospects45. Prospective Advances in Medical Epigenetics
- ISBN: 978-0-12-803239-8
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 900
- Fecha Publicación: 13/07/2016
- Nº Volúmenes: 1
- Idioma: Inglés