Biocatalysis based on heme peroxidases: peroxidases as potential industrial biocatalysts

This monograph describes many applications of peroxidase-based biocatalysis in the biotechnology industry. The need for such a book emerges from the considerable amount of new data regarding the phylogeny, reaction mechanisms, thermodynamic characterization and structural features of fungal and plant heme peroxidases that has been generated in the past 10 years, since the last specialized book on peroxidases was published. The aim of this book is to present recent advances on such basic aspects as evolution, structure-function relation andcatalytic mechanism as well as applied aspects, such as bioreactor and protein engineering, to provide the tools for rational design of enhanced biocatalysts and biocatalytic processes. - First monograph on the subject for 10 years -Especially covers the application in the biotechnology industry including thelimitations - summarizes new data. INDICE: 1.-Introduction MOLECULAR AND STRUCTURAL ASPECTS OF PEROXIDASES 2.- Molecular phylogeny of heme peroxidases (Marcel Zámocký and Christian Obinger) 3.- Structural and functional features of peroxidases with a potential as industrial biocatalysts (Francisco J. Ruiz-Dueñas and Angel T. Martínez) 4.-Redox potential of heme peroxidases (Marcela Ayala) 5.- Catalytic mechanisms of heme peroxidases (Paul R. Ortiz de Montellano) PROSPECTIVE USAGE OF PEROXIDASESIN INDUSTRY 6.- Potential applications of peroxidases in the fine chemicals industry (Luigi Casella, Enrico Monzani and Stefania Nicolis) 7.- Grafting of functional molecules: insights into peroxidase-derived materials (Gibson S. Nyanhongo, Endry Nugroho Prasetyo, Tukayi Kudanga and Georg Guebitz ) 8.- Applications and prospective of peroxidase biocatalysis in the environmental field (Cristina Torres-Duarte and Rafael Vazquez-Duhalt) CHALLENGES IN THE APPLICATIONOF PEROXIDASES 9.-Enzyme technology of peroxidases: immobilization, chemical and genetic modification (Adriana Longoria, Raunel Tinoco and Eduardo Torres).10.- Reactor engineering (Juan M. Lema, Carmen López, Gemma Eibes, Roberto Taboada-Puig, M. Teresa Moreira and Gumersindo Feijoo) 11.- Deactivation of hemeperoxidases by hydrogen peroxide: focus on Compound III (Brenda Valderrama) 12.- Heterologous expression of peroxidases (Sandra de Weert and B. Christien Lokman) 13.- A compendium of bio-physical-chemical properties of peroxidases (Humberto García-Arellano)

• ISBN: 978-3-642-12626-0
• Editorial: Springer
• Encuadernacion: Cartoné
• Páginas: 325
• Fecha Publicación: 01/08/2010
• Nº Volúmenes: 1
• Idioma: Inglés