Handbook of Immunoassay Technologies: Approaches, Performances, and Applications
Vashist, Sandeep K.
Luong, John H.T.
Immunoassays play a prominent role in clinical diagnostics as they are the eyes of healthcare professionals, who helps them to make informed clinical decisions via confirmed disease diagnosis, thereby enabling favorable health outcomes. Therefore, the higher is the specificity and sensitivity of the immunoassays and the lower are their response time, complexity and costs, the higher is their potential for healthcare monitoring and disease management. The faster and reliable diagnosis of infections will further control their spread to uninfected persons. Similarly, immunoassays play a prominent role in veterinary diagnostics, food analysis, environmental monitoring, defense and security, and other bioanalytical settings. Therefore, they enable the detection of a plethora of analytes, which includes disease biomarkers, pathogens, drug impurities, environmental contaminants, allergens, food adulterants, drugs of abuse and various biomolecules. Immunoassay Analyzers: State-of-the-art and future prospects unravels the role of immunoassays in biochemical sciences. During the last four decades, a wide range of immunoassays has been developed, which range from the conventional enzyme-linked immunosorbent assays to the smartphone-based point-of-care formats. The advances in rapid biochemical procedures, novel biosensing schemes, fully integrated lab-on-a-chip platforms, prolonged biomolecular storage strategies, device miniaturization and interfacing, and the emerging smart system technologies equipped with personalized mobile healthcare tools are paving the way to next-generation immunoassays. Provides a valuable increase of understanding of cellular and biomedical functionsGives the most updated resource in the field of immunoassays, which provides the comprehensive details of various types of immunoassays that need to be performed in healthcare, industrial, environmental and other biochemical settingDiscussed all multifarious aspects of immunoassaysComprehensively describes the immunoassay formats along with their principle of operation, characteristics, pros and cons, and potential biochemical and bioanalytical applicationsTakes all types of immunoassays into account developed to date and the various aspects of immunoassay, thereby providing the most updated resource for professionals, researchers, and students, who are already working or want to work in the field of immunoassaysProvides extensive knowledge and guided insights as it is written by renowned experts and key opinion makers in the field of immunoassays, who have extensive experience in this field INDICE: 1. Immunoassays: An overview 2. Antibody immobilization and surface functionalization chemistries 3. Enzyme-linked immunoassays 4. Surface Plasmon Resonance-based immunoassays 5. Lab-on-a-chip based immunoassays 6. Smartphone based Immunoassays 7. Lateral flow immunoassays 8. Paper-based immunoassays 9. Nano- and Micro-materials based immunoassays 10. Electrochemical immunoassays 11. Turbidimetric immunoassays 12. Mass spectroscopy based immunoassays 13. Immunoaffinity chromatography based immunoassays 14. Interferometry based immunoassays 15. Microcantilever based immunoassays 16. Quartz crystal microbalance based immunoassays 17. Surface acoustic wave based immunoassays 18. Point-of-care immunoassays 19. Evaluation, quality control and troubleshooting of immunoassays 20. Healthcare, industrial and regulatory requirements for immunoassays
- ISBN: 978-0-12-811762-0
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 515
- Fecha Publicación: 01/03/2018
- Nº Volúmenes: 1
- Idioma: Inglés