Spinal Cord Injury: Handbook of Clinical Neurology Series

Spinal Cord Injuries, the newest volume in the Handbook of Clinical Neurology series, offers a comprehensive and detailed overview of the rapidly evolving science and treatment of spinal cord injury. Advances in neuroimaging, surgical treatment and application of electrical stimulation are dramatically impacting the treatment and outcome of these injuries. It provides a clear introduction to the core science of spinal cord injury, as well as to exciting research investigating new treatment options. Coverage includes brain-machine interfaces, transcranial stimulation, new pharmacological strategies, use of olfactory ensheathing cells, stem cells and precursor cells, gene therapy and molecular target discovery. This volume is a great resource for neuroscience and clinical neurology research specialists and practicing neurologists seeking a clear reference to the science and treatment of spinal cord injury. *Comprehensive coverage of the latest scientific understanding of spinal cord injuries*Detailed coverage of current treatment best practices and potential future treatments*Connects leading edge research programs to future treatment opportunities INDICE: SECTION 1 Developmental and Anatomical Perspectives 1. Development and maturation of the spinal cord: implications of molecular and genetic defects; 2. Anatomy and biomechanics of the spinal column and cord SECTION 2 Diagnosis and Prognosis 3. Clinical diagnosis and prognosis following spinal cord injury; 4. Clinical neurophysiology in the prognosis and monitoring of traumatic spinal cord injury; 5. Concepts of aging with paralysis: implications for recovery and treatment; 6. Advanced MRI strategies for assessing spinal cord injury SECTION 3 Acute Spinal Cord Injury: Medical, Surgical and Rehabilitative Management 7. Advances in the management of spinal cord and spinal column injuries; 8. Spinal cord injuries in children and adolescents; 9. The changing landscape of spinal cord injury; 10. Surgical treatments to restore function control in spinal cord injury; 11. Advances in the rehabilitation management of acute spinal cord injury; 12. Spasticity; 13. Disordered cardiovascular control after spinal cord injury; 14. New concepts in the prevention of pressure sores; 15. Functional electrical stimulation for bladder, bowel and sexual function; 16. Evidence based therapy for recovery of function after spinal cord injury; 17. Functional electrical stimulation: restoration of respiratory function; 18. Spinal cord stimulation: therapeutic benefits and movement generation after spinal cord Injury; 19. Promoting optimal functioning in spinal cord injury: the role of rehabilitation psychology SECTION 4 Chronic Spinal Cord Injury - The Changing Perspective of Neurorestorative Rehabilitation, Activity-Based and Surgical Restoration Therapies 20. The changing field of rehabilitation: optimizing spontaneous regeneration and functional recovery; 21. The longitudinal spinal cord injury: lessons from intra spinal plexus, cauda equina and medullary conus lesions; 22. Post-traumatic syringomyelia; 23. Post-traumatic deformity: prevention and management SECTION 5 Preclinical Research - Bridging the Gap Between Bench and Bedside 24. Spinal cord injury clinical trials: translational process, review of past and proposed acute trials with reference to recommended trial guidelines; 25. Translating preclinical approaches into human application; 26. Translational spinal cord injury research: preclinical guidelines and challenges; 27. Brain-machine interfaces and transcranial stimulation: future implications for directing functional movement and improving function after spinal injury in humans; 28. Approaches to repairing the damaged spinal cord: overview; 29. Limiting spinal cord injury by pharmacological intervention; 30. Harmful and beneficial effects of inflammation after spinal cord injury: potential therapeutic implications; 31. Defeating inhibition of regeneration by scar and myelin components; 32. Realising the maximum potential of Schwann cells to promote recovery from spinal cord injury; 33. Repair of CNS lesions by transplantation of olfactory ensheathing cells; 34. Cell transplantation: stem cells and precursor cells; 35. Gene therapy, neurotrophic factors and spinal cord regeneration; 36. Scaffolds to promote spinal cord regeneration; 37. Molecular target discovery for neural repair in the functional genomics era; 38. Combination therapies

• ISBN: 978-0-444-52137-8
• Editorial: Elsevier
• Encuadernacion: Cartoné
• Páginas: 656
• Fecha Publicación: 26/11/2012
• Nº Volúmenes: 1
• Idioma: Inglés