Animal Biotechnology: Models in Discovery and Translation

Animal Biotechnology introduces applications of animal biotechnology and implications for human health and welfare. It begins with an introduction to animal cell cultures and genome sequencing analysis and provides readers with a review of available cell and molecular tools. Topics here include the use of transgenic animal models, tissue engineering, nanobiotechnology, and proteomics. The book then delivers in-depth examples of applications in human health and prospects for the future, including cytogenetics and molecular genetics, xenografts, and treatment of HIV and cancers. All this is complemented by a discussion of the ethical and safety considerations in the field. Animal biotechnology is a broad field encompassing the polarities of fundamental and applied research, including molecular modeling, gene manipulation, development of diagnostics and vaccines, and manipulation of tissue. Given the tools that are currently available and the translational potential for these studies, animal biotechnology has become one of the most essential subjects for those studying life sciences. Highlights the latest biomedical applications of genetically modified and cloned animals with a focus on cancer and infectious diseasesProvides firsthand accounts of the use of biotechnology tools, including molecular markers, stem cells, and tissue engineering INDICE: Section I: Essentials of Animal Biotechnology Hybridoma Technology; Animal cell culture; Genetic engineering and transgenic animal model for biomedical research; Quantitative analysis of brain gene expression; Marine animal biotechnology; scope and prospects; Genome sequencing and analysis; Biosafety levels; Section II: Tools of Animal Biotechnology Molecular markers and their advances in genetic analysis of laboratory animals; Development and exploitation of animal model to understand pathogenesis of infectious disease; Stem cell; CAM Assay as a model for angiogenesis; Electrophysiology and animal tissue engineering; ADME; Concepts of tissue engineering; Nanobiotechnology and its applications; Proteomics and its application Section III: Applications of Animal Biotechnology Immunodiagnosis of filariasis; Biomedical applications of genetically modified and cloned animals; Drosophila rosetta for studying genetics and development; Immunobiotechnology; Gene therapy Section IV: Role of Animal Biotechnology in Human Health HIV; Utility of mouse tumor xenograft model, discovery and  development of novel therapeutics against cancer stem cells; Role of cytogenetics and molecular genetics in medicine; Clinico-molecular approaches for detection of HPV; Human DNA tumor viruses & oncogenesis Section V: Concerns of Animal Biotechnology Safety assessment of genetically modified crop derived food; Ethical issues in animal biotechnology; Ethics in biotechnology;  IPR; Ethnobotanical wisdom and search for new drugs: Opportunities and challenges.

• ISBN: 978-0-12-416002-6
• Editorial: Academic Press
• Encuadernacion: Cartoné
• Páginas: 668
• Fecha Publicación: 06/01/2014
• Nº Volúmenes: 1
• Idioma: Inglés