Within the complex neuronal network of the nervous system, neuron-to-neuron communication occurs mainly through chemical synapses, where the presynaptic nerve terminal releases neurotransmitters which control the function of postsynaptic neurons by acting on postsynaptic receptors. Recent decades have brought ground-breaking new developments and a wealth of knowledge to this field. In 'Molecular Mechanisms of Neurotransmitter Release', leading experts provide concise, up-to-date information on all major molecular mechanisms involved, with complete background information and figures and diagrams to further elucidate key concepts or experiments. Comprehensive and cutting-edge, 'Molecular Mechanisms of Neurotransmitter Release' is sure to provide a learning tool for neuroscience students, a solid reference for neuroscientists, and a source of knowledge for all those who have a general interest in the ever-evolving field of neuroscience Up-to-date, systematic, and in-depth reviews on molecular mechanisms of neurotransmitter release Sufficient background information to suit a broad readership List of comprehensive index words for easy look-up Diagrams and figures in enclosed CD for use in teaching INDICE: The Architecture of the Presynaptic Release Site.- Multiple modes of fusion and retrieval at the calyx of Held synapse.- Roles of SNARE proteinsin synaptic vesicle fusion.- Roles and sources of calcium in synaptic exocytosis.- Regulation of presynaptic calcium channels.- Synaptotagmin: transducing Ca2+-binding to vesicle fusion.- Functional interactions between the SNARE regulators UNC-13, tomosyn and UNC-18.- Roles of the ELKS/CAST family and SAD kinase in Neurotransmitter Release.- The role of potassium channels in the regulation of neurotransmitter release.- Modulation of neurotransmitter release and presynaptic plasticity by protein phosphorylation.
- ISBN: 978-1-934115-38-1
- Editorial: Humana
- Encuadernacion: Cartoné
- Páginas: 350
- Fecha Publicación: 01/10/2008
- Nº Volúmenes: 1
- Idioma: Inglés