Protein chaperones and protection from neurodegenerative diseases

ÍNDICE: 1. Intrinsically disordered chaperones and neurodegeneration (Uversky). 2. Redox Regulation of Protein Misfolding, Synaptic Damage, and Neuronal Loss in Neurodegenerative Diseases (Lipton). 3. Chaperone-mediated autophagy and Parkinsons disease (Wong). 4. Chaperone and anti-chaperone properties of synuclein: implications for development, aging and neurodegenerative disease (Hashimoto). 5. The ubiquitin proteasome system in neurodegenerative diseases: More than the usual suspects (Bertolotti). 6. Regulation of the polyglutamine androgen receptor by the Hsp90/Hso70-based chaperone machinery (Lieberman). 7. Amyloid remodeling by Hsp 104 (Shoter). 8. Chaperone-Dependent Amyloid Assemblyand Prion Toxicity (Cyr). 9. Modulation of amyloid propagation in yeast by Hsp70 and its regulators and chaperone partners (Masison). 10. ALS and the copper chaperone CCS (Elliot). 11. Emerging Area: TorsinA, an Novel ATP-Dependent Factor Linked to Dystonia (Zolkiewski). 12. Therapeutics: harnessing the power of protein and pharmacological chaperones (Witt).

• ISBN: 978-0-470-56907-8
• Editorial: John Wiley & Sons
• Encuadernacion: Cartoné
• Páginas: 452
• Fecha Publicación: 29/07/2011
• Nº Volúmenes: 1
• Idioma: Inglés