Polyamine drug discovery covers a number of validated drug targets, includingenzymes in the polyamine biosynthetic and catabolic pathways and the S-adenosylmethionine synthetic and salvage pathways. This is the first book to providea comprehensive description of polyamine drug discovery, and the utility of polyamine analogues in the treatment of disease. It includes chapters written by medicinal or biological chemists describing their approaches to developing agents that modulate polyamine metabolism or function. These chapters focus on the discovery of polyamine-based analogues for use as antitumor and anti-infective agents. The book will increase the visibility of polyamine drug discoveryamong pharmaceutical researchers and provide a valuable reference for everyone working in the polyamine field.
- ISBN: 978-1-84973-190-4
- Editorial: Royal Society of Chemistry
- Encuadernacion: Cartoné
- Fecha Publicación: 31/08/2011
- Nº Volúmenes: 1
- Idioma: Inglés